Hemophilia B

A deficiency of blood coagulation factor IX inherited as an X-linked disorder. (Also known as Christmas Disease, after the first patient studied in detail, not the holy day.) Historical and clinical features resemble those in classic hemophilia (HEMOPHILIA A), but patients present with fewer symptoms. Severity of bleeding is usually similar in members of a single family. Many patients are asymptomatic until the hemostatic system is stressed by surgery or trauma. Treatment is similar to that for hemophilia A. (From Cecil Textbook of Medicine, 19th ed, p1008)

Also Known As:

Haemophilia B; Christmas Disease; Factor IX Deficiency; Deficiency, Factor IX; F9 Deficiency; Hemophilia B Leyden; Hemophilia B(M); Plasma Thromboplastin Component Deficiency; Bs, Hemophilia; Deficiencies, F9; Deficiencies, Factor IX; Deficiency, F9; Disease, Christmas; F9 Deficiencies; Factor IX Deficiencies; Haemophilia Bs; Hemophilia Bs; Hemophilia Bs (M)

Hemic and Lymphatic Diseases: 7
- Hematologic Diseases: 3445
  - Hemorrhagic Disorders: 706
    - Hemophilia B: 1944
  - Blood Coagulation Disorders: 168
    - Inherited Blood Coagulation Disorders: 76
      - Hemophilia B: 1944
    - Coagulation Protein Disorders: 1
      - Hemophilia B: 1944
Congenital, Hereditary, and Neonatal Diseases and Abnormalities: 960
- Inborn Genetic Diseases: 12342
  - Inherited Blood Coagulation Disorders: 76
    - Hemophilia B: 1944
  - X-Linked Genetic Diseases: 42
    - Hemophilia B: 1944

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Disease

Drug/Important Bio-Agent (IBA)